Suzuko Homura and Chinatsu Morikawa's victory against the nefarious Bookmaker Kou Satomi has allowed the two girls to finally return to a life of normalcy and seize the chance to move on. However, the peace does not last long, as Kiyoi Mizushima requests Suzuko's help to prevent the next cycle of Selector battles; even after Satomi's defeat, efforts to continue his plans seem to persist. Troubled by lingering doubts and the unresolved situation, Suzuko decides to assist Mizushima with her investigation—unknowingly becoming involved in the escalating fight that will determine the fate of Selectors once and for all.

It's sometime in the future and the story starts off with Kei and Ai running for their lives. Ai is a little girl who holds a terrible secret which could destroy the current world. The world is now populated by Headmeters, people who have psychic powers and their strength is shown on their forehead when they fight. However, Kei was an experimental subject and his strength never went above level 5 while other surpasses his ability effortlessly. While escaping, when in desperate moments, Kei could increase his ability to infinity when Ai is in trouble. The one who's after her have a deep secret, aided by a small dwarflike man living in a robotic suit. Eventually Ai is captured and Kei, a sherlock holmes detective and another Headmeter who was converted to the good side when Kei unleashed his horrible powers through Ai must go and rescue her. Together they must save Ai and the secret which she holds. What is the secret of Ai? Who is she?

27-year-old Tokyo office worker Mire Yoshizuki just returned to Japan, while 22-year-old fourth-year college student Sora Nagase aspires to be a teacher, and 20-year-old boyish Reika Kawatani is a part-time Hiroshima okonomiyaki shop worker and freelancer. What draws together these three women from completely different walks of life is a magic gem. A "New Magical Story" begins when they are mysteriously brought together by chance and embark on a journey.

After contracting hepatitis A, Ezaki Yuuichi has been confined to a hospital, away from his friends and family, much to his displeasure. To relieve his boredom, he has taken to sneaking out of the hospital, usually putting himself on the receiving end of a beating from his nurse. Upon meeting a girl his age also staying in the hospital, he is immediately captivated by her beauty. Akiba Rika's personality is not quite as captivating as her beauty however. In fact, she is rather selfish, moody, and bossy. But as the two spend more time with each other, they become closer, sharing the ordinary joys and trials of a budding teenage romance, even when darkened with impending tragedy—for Rika's condition does not leave her much longer to live.