Saikin, Imouto no Yousu ga Chotto Okashiinda ga. follows a family just starting to rebuild. When they marry, Mr. and Mrs. Kanzaki bring a teenage son and daughter along for the ride. But high school freshman Mitsuki Kanzaki is less than thrilled. Stinging from a history of absent and abusive father figures, she is slow to accept her stepfather and stepbrother. But after an accident lands Mitsuki in the hospital, she finds herself possessed by the ghost of Hiyori Kotobuki, a girl her age who was deeply in love with Mitsuki's stepbrother Yuuya. Hiyori cannot pass on to her final reward because of her unrequited love for Yuuya, meaning she's got to consummate it... in Mitsuki's body?! Now, Mitsuki's life depends on getting Hiyori to Heaven. But will she get used to sharing herself with a pushy, amorous ghost? Can she overcome her distrust of her new family? Can she bring herself to fulfill Hiyori's feelings for Yuuya? And might she be hiding some feelings of her own?

The story starts off with a face-off between two rival heroes, ZET and ALPHAS, and then traces their origins - Jin Kanzaki, a young man with the ability to transform into a superhuman being known as ZET, and Kouga Amagi, a young man with a strong sense of justice who uses technology to fight as ALPHAS. The fates of these two men and those around them intertwine as they fight to protect mankind and destroy monstrous abominations known as Players. (Source: ytv ENGLISH)

In a not-too-distant future, humanity has established a loosely organized world government with everything managed by an international AI network called Sapientia. People live peaceful lives by loyally obeying its rational decisions. However, Sapientia's lunar development project, which sends criminals and pollutants to the Moon to maintain Earth's peace, creates disparity and poverty on the Moon, sparking a catalyst for war. Jacob "Jack" Shadow gets caught up in this conflict after losing his family to a terrorist bombing by the Moon's rebel army. Vowing revenge, Jack joins the Earth army as a scout on the Moon, only to discover an unexpected leader among the resistance forces.

Nagumo Keeichirou was a genius high-school detective. No case was complex enough for him. But what happens to genius detectives when they get older? Now 35, with bad hips, running a failing detective agency with no cases to solve and struggling to pay the rent, he's at a dead end. In comes a high school girl in his office who says she wants to work with him. With her help, will the out-of-touch, old-fashioned Nagumo get back the fire of his youth?