Fumiya Tomozaki is Japan's best player in the online game Attack Families, commonly known as "Tackfam." Despite holding such a revered title, a lack of social skills and amiability causes him to fall short in his everyday high school life. Failing to have any friends, he blames the convoluted mechanics and unfair rules of life, forcing him to give up and proclaim himself a bottom-tier character in this "game." After a fateful meeting with another top-tier Tackfam player, Fumiya is shocked to discover the player's true identity—Aoi Hinami, a popular, smart, and sociable classmate who is the complete opposite of himself. Aoi, surprised at how inept Fumiya is at everything besides Tackfam, decides to assist him in succeeding in what she calls the greatest game of them all. Through the gruesome ordeals of social interactions and relationships, Fumiya begins to advance tiers in the glorious game of life. [Written by MAL Rewrite]

After achieving fruitful results in New World Online's previous events, the now famous Maple Tree guild is excited to explore the new floors introduced in game. As if their guild was not already feared enough, each member is motivated to find stronger skills for themselves in order to greatly expand their options in future battles. Not forgetting the importance of networking, the guild also forges amicable relationships with other notable guilds, such as the Kingdom of the Flame Emperor and the Congregation of the Holy Swords. With their eccentric guild master Maple at the forefront, the members of Maple Tree continue to stumble upon creative ways to implement their skills, driving the game developers crazy along the way.

Takuma Sakamoto is a hikikomori gamer who is mysteriously transported to the virtual world of his favourite MMORPG, Cross Reverie, with the appearance of his own character in the game, the Demon Lord Diablo. The two young girls who summoned him, the pantherian Rem and the elf Shera, attempt to use a spell to make Takuma their servant, but due to his magic ring with the ability "Magic Reflection", the spell rebounds, and both end up with magic collars stuck on their necks, thus becoming his servants instead. With a serious case of social anxiety, Takuma decides to act like his character while interacting with others, and makes use of his high stats and vast knowledge of Cross Reverie's lore to survive in his new environment, traveling along with Rem and Shera to look for a way to remove their slave collars, while helping them with their own personal issues that led them to summon him in the first place.

High schooler Hayase Nagatoro loves to spend her free time doing one thing, and that is to bully her Senpai! After Nagatoro and her friends stumble upon the aspiring artist's drawings, they find enjoyment in mercilessly bullying the timid Senpai. Nagatoro resolves to continue her cruel game and visits him daily so that she can force Senpai into doing whatever interests her at the time, especially if it makes him uncomfortable. Slightly aroused by and somewhat fearful of Nagatoro, Senpai is constantly roped into her antics as his interests, hobbies, appearance, and even personality are used against him as she entertains herself at his expense. As time goes on, Senpai realizes that he doesn't dislike Nagatoro's presence, and the two of them develop an uneasy friendship as one patiently puts up with the antics of the other.