Kanna loses her love of running after her mother passes away. Due to the workings of the gods, she heads to Izumo City.

When Keyaru acquired his powers as a Hero who specialized in healing all injuries regardless of severity, it seemed that he would walk the path to a great future. But what awaited him instead was great agony; he was subjected to years of seemingly endless hellish torture and abuse. Keyaru's healing skills allowed him to secretly collect the memories and abilities of those he treated, gradually making him stronger than anyone else. But by the time he reached his full potential, it was far too late—he had already lost everything. Determined to put his life back on track, Keyaru decided to unleash a powerful healing spell that rewound the entire world back to the time before he began to suffer his horrible fate. Equipped with the anguish of his past, he vows to redo everything in order to fulfill a new purpose—to exact revenge upon those who have wronged him. [Written by MAL Rewrite]

As long as hearts exist inside people, there will always be those who suffer. And then something "strange" enters their mind and causes a strange disease to manifest itself in the body. The illness, which is called a "mystery disease" is unknown to most, but certainly exists. There is a doctor and apprentice who fights the disease, which modern medicine cannot cure. His name is Ramune. He acts freely all the time, is foul-mouthed, and doesn't even look like a doctor! However, once he is confronted with the mysterious disease, he is able to quickly uncover the root cause of his patients' deep-seated distress and cure them. And beyond that... (Source: Crunchyroll)

A stubborn girl on a mysterious island, her dreams of becoming a martial artist, and her complicated love story.