Thirty years ago, the Eurasian continent was devastated by a supermassive "spatial quake"—a phenomenon involving space vibrations of unknown origin—resulting in the deaths of over 150 million people. Since then, these quakes have been plaguing the world intermittently, albeit on a lighter scale. Shidou Itsuka is a seemingly average high school student who lives with his younger sister, Kotori. When an imminent spatial quake threatens the safety of Tengu City, he rushes to save her, only to be caught in the resulting eruption. He discovers a mysterious girl at its source, who is revealed to be a "Spirit," an otherworldly entity whose appearance triggers a spatial quake. Soon after, he becomes embroiled in a skirmish between the girl and the Anti-Spirit Team, a ruthless strike force with the goal of annihilating Spirits. However, there is a third party that believes in saving the spirits: "Ratatoskr," which surprisingly is commanded by Shidou's little sister! Kotori forcibly recruits Shidou after the clash, presenting to him an alternative method of dealing with the danger posed by the Spirits—make them fall in love with him. Now, the fate of the world rests on his dating prowess, as he seeks out Spirits in order to charm them. [Written by MAL Rewrite]

Lucy is a special breed of human referred to as "Diclonius," born with a short pair of horns and invisible telekinetic hands that lands her as a victim of inhumane scientific experimentation by the government. However, once circumstances present her an opportunity to escape, Lucy, corrupted by the confinement and torture, unleashes a torrent of bloodshed as she escapes her captors. During her breakout, she receives a crippling head injury that leaves her with a split personality: someone with the mentality of a harmless child possessing limited speech capacity. In this state of instability, she stumbles upon two college students, Kouta and his cousin Yuka, who unknowingly take an injured fugitive into their care, unaware of her murderous tendencies. This act of kindness will change their lives, as they soon find themselves dragged into the shadowy world of government secrecy and conspiracy. [Written by MAL Rewrite]

After a routine raid, the rookie sky pirate Coud finds a most unusual cargo in his mates' cargo hold: Ren, an "Edel Reid", a race prized by humans for granting special combat power to their partners through "Reacting". He quickly discovers, however, that Ren is even more prized than he expected. The pirate ship is visited by three members of the Edel Reid Complete Protection Agency "Arc Aire", who try to purchase her. When Coud refuses, the ship is suddenly attacked by a mysterious force, and Coud's captain charges him with Ren's protection. (Source: ANN)

Straightforward and innocent Hisone Amakasu is a Self-Defense Force rookie stationed at the Air Self-Defense Force's Gifu Base. She was struggling with the fact that she sometimes hurts people unintentionally by her innocent words and decided to join the Air Self-Defense Force, hoping to maintain a certain distance from people. This decision led her to a fateful encounter which profoundly changed her life. It was the "OTF" dragon hidden in the base and it chose Hisone as his pilot. When it soared into the sky with Hisone, her fate as a dragon pilot was decided. It is said that dragons have a key to the future of the world... (Source: ANN)