In deep space a battle wages between the forces of good and evil and the fate of the Earth hangs in the balance. The evil Neos Gold dispatches her invading forces towards Earth with only one aim: the total destruction of all mankind. Now it's up to Iczer 3 (the younger sister of Iczer 1) to defend the Earth from the deadly armada of Neos Gold, with only the Earth's single remaining battle cruiser on her side. But don't count her out; what Iczer 3 lacks in experience she makes up for in all-out enthusiasm.

Malice, a sex robot living in an abandoned human city, is assaulted and violated by a mysterious creature. Upon awakening, Malice finds out that she has become human and can pass on her humanity to her fellow machines. However, her gift soon becomes a curse when her fellow robots rage out of control after being exposed to the pleasures of life.

As the nations of the world begin to merge, world peace is threatened by the private armies of individual corporations. The Kuryu Group has just discovered a weapon that will tip world power in their favor. The Genocyber: a nightmarish combination of cybernetics and psychic potential. Many desire to control this monstrosity, but can its hatred be contained... Battle erupts, and the cyberpunk world of the future is about to explode with violence. (Source: ANN)

The story is centered around Filena, a princess who was raised as a boy after her kingdom was conquered.