As with both the Advanced Generation and Diamond & Pearl series before it, the Best Wishes! series begins with only Satoshi, headed off to the Isshu region, located far away from Kanto, Johto, Houen, and Sinnoh, with his Pikachu. After he meets up with the new trainer and rival Shooty and the region's Professor Araragi, he gains traveling companions in Iris, a girl from a town known for its Dragon Pokémon, and Dent, Pokémon Connoisseur and the Grass Pokémon specialist of the three Sanyou City Gym Leaders.

For Hikari Tsutsui, life within the two-dimensional realm is much simpler. Socially inept and awkward, he immerses himself in video games and anime, only to be relentlessly ridiculed and ostracized by his classmates. Sharing his misery is Yuuto Itou, his only friend, who wears cat ears and is equally obsessed with the world of games. After being forced to clean the pool as punishment for arriving late, Tsutsui meets Iroha Igarashi, but he attempts to steer clear of her, as her notoriety precedes her. Brazenly blunt, loathed by female classmates, and infamous for messing around with boys, Tsutsui believes that getting involved with her would cause nothing but problems. 3D Kanojo: Real Girl is a story revolving around these two outcasts—a boy full of emotions he has never experienced before, struggling to lay them bare, and a girl who strives to break him out of his shell. [Written by MAL Rewrite]

Gakusen Toshi Asterisk 2nd Season continues the story of Genestella students Ayato Amagiri and Julis-Alexia von Riessfeld, who have progressed to the next round of the Phoenix Festa after a long and strenuous battle with sisters Irene and Priscilla Urzaiz. Despite Julis and Ayato's best attempts, the fact that Ayato's powers have been sealed is no longer a secret. Now at a major disadvantage, the duo must come up with a plan if they are to have any hope of winning the Phoenix Festa. Only one thing is for sure: the troubles heading their way are only going to get more insurmountable from here on. [Written by MAL Rewrite]

Ever since he was a child, zombie-obsessed Chihiro Furuya has wanted an undead girlfriend. Soon enough, his love for all things zombie comes in handy when his cat Baabu gets run over, prompting Chihiro to try to make a resurrection potion and bring him back to life. During his endeavor, he sees a rich girl named Rea Sanka yelling into an old well every day about her oppressive life. After meeting and bonding with her, Chihiro is convinced by Rea to persevere in saving Baabu. Eventually, he succeeds with the help of the poisonous hydrangea flowers from Rea's family garden. Unaware of the potion's success and seeking to escape the burdens of her life, Rea drinks the resurrection potion, mistakenly thinking she will die. Though it doesn't kill her, the effects still linger and her death from a fatal accident causes her to be reborn as a zombie. With help from Chihiro, Rea strives to adjust to her new—albeit undead—life. For a boy wanting a zombie girlfriend, this situation would seem like a dream come true. But in Sankarea, Chihiro's life becomes stranger than usual as he deals with Rea's odd new cravings and the unforeseen consequences of her transformation. [Written by MAL Rewrite]