Joutarou Kuujou and his allies have finally made it to Egypt, where the immortal Dio awaits. Upon their arrival, the group gains a new comrade: Iggy, a mutt who wields the Stand "The Fool." It's not all good news however, as standing in their path is a new group of Stand users who serve Dio, each with a Stand representative of an ancient Egyptian god. As their final battle approaches, it is a race against time to break Joutarou's mother free from her curse and end Dio's reign of terror over the Joestar family once and for all.

On the dusty streets of the castle town Dayah in the Fortna Kingdom, a young orphan named Nina steals for survival. Experiencing one tragedy after another, she has little to hope for in her life. Believing it best for Nina, her closest friend, Saji, hands her over to Second Prince Azure Seth Fortna, who has been searching for someone with unique and intense deep-blue eyes—just like Nina's. The kingdom's princess, the revered Astral Priestess Alisha, has recently died on her way to the Galgada Kingdom, where she was to marry the tyrant First Prince Sett. However, her death is concealed for political reasons, and that is where Nina needs to step in. With nowhere else to go and no one to turn to, Nina assumes Alisha's identity and future duties. But with each moment spent with Azure, Nina feels herself drawn to his warmth, fearing that once she is wed to another, nobody will remain to remember her true self.

When the gods would not answer in humanity's desperate hour of need, it turned to a demon instead. The supposed savior came wielding the sword Zsoltgewinn, but its uncontrollable lust for blood led it to kill those who summoned it too. Although the sword was sealed away long ago, it has been uncovered by the Shoshidai, an organization that collects such cursed artifacts. However, Zsoltgewinn proves to be too strong to be tamed by humans when its corruptive power influences the administrator, Takuma Miura, to flee with it in his grasp. At the same time, Gai Ogata's family is torn apart due to the possession of another demonic sword, Shiryu, leading his father to be murdered and his mother to hang herself shortly after giving birth to him. Abandoned in the forest clutching the blade, he is discovered by the blacksmith Amon. Unnaturally transfixed by the sword, Gai works tirelessly for years to hone his smithing skills. However, when an accident costs him his arm, he gains a new one—in the form of a reforged Shiryu. Now having a cursed sword for an arm, Gai must learn to control its violent urges. All the while, Zsoltgewinn continues its rampage, leaving a path of blood in its wake. [Written by MAL Rewrite]

Touka Kuroizu is a research assistant who belongs to the Monster Development Department of the evil organization Agastia. However, the enemy she has to fight right now isn't the heroes of justice, but her boss. So long justice exists, evil too, will exist. This is the story of those who fight secretly in the shadows of justice and evil's confrontation.