Second season of Shaonian Ge Xing. Don't be afraid of failure. Don't waste your youth. After Xiao Se and Lei Wujie came to Snow and Moon City, Sikong Changfeng forcibly took Xiao Se as his apprentice. Lei Wujie and Li Hanyi recognized each other. As Xiao Se entered Snow and Moon City, other princes of Tianqi were eager to seek allies. A battle between princes slowly started at the hero banquet in Lei Jia Bao.

Mami Sakura used to be a normal junior high school student, but she happened to acquire supernatural powers. Using her powers and with the help of her best friend, Mr. Takahata, she solves mysterious occurrences. When she senses someone needs help, she uses the "Teleportation Gun" and transports herself there. She then saves the world in trouble with her psychic powers, such as telekinesis and telepathy.

In Tenikai General Hospital's general diagnostic department, patients who are deemed difficult to treat by other doctors are collected here. From mysteries of unknown illness to murders that even the police can't handle. Genius doctor Takao Ameku reveals the shocking truth hidden behind these mysterious "disease."