Amawa Hibiki is a young man just out of college, with an education to be an athletics teacher. He's been having a hard time finding a job since he graduated, so all his money has gone towards living expenses. When his landlady demands his first payment to live in her living establishment upfront, he heads to the local middle school to get hired as a teacher. However, the principal refuses to hire him without hesitation. She will not hire men as teachers and makes it clear that she hates all men, saying they put no love into their passions and work. Amawa does not give up and with the help of his landlady, he crossdresses as a woman without a second thought, and gets hired, so he can earn money and also prove the principal wrong. Now, he has to keep his real gender a secret, and avoid strange situations, including the affections of his students (from both genders).

The skilled craftsman Kuroda created artificial humans called Hybrid Child—creatures who are neither machines nor dolls, but rather a reflection of the love shown to them. While they can feel human emotions and have their own consciousness, they are not real humans and require love to grow. Kotarou Izumi is the young heir to the noble Izumi family, so it is frowned upon when he brings an abandoned Hybrid Child he found in the garbage into their household. His family even attempts to throw away Hazuki—Kotarou's name for the Hybrid Child—multiple times when he is not paying attention. But through overcoming these obstacles, their love and the bond connecting them grow stronger. However, ten years pass before a horrifying realization dawns on them: a Hybrid Child might not have an endless life span. Hybrid Child is a collection of three short love stories, depicting the relationship between the artificial humans and their owners.

19-year old Reiko is a rich, arrogant, material girl, who refuses to admit her feelings for classmate Tetsuya Akimoto before it's almost too late. Reiko pursues him to Tokyo and enrolls at his university in an attempt to win him back.

Brother and younger sister-in-law live in the house which parents are often away from. Yuki who is the younger sister is secretly yearning for Kenji who is the elder brother. However, one girl came to show up from the closet in Kenji's room after a certain night. Moreover, her body is transparent, and she looks like the ghost. Her name is Hiyori. She is a friend in their childhood. They are pleased with reunion though Kenji and Yuki are perplexed with the way of Hiyori's strange appearance. However, Yuki gets the mind shaken as Kenji and Hiyori become intimate, and the pain in her mind in the childhood is recalled. At the childhood, Yuki was going to pass the light blue toy ring which Kenji had had to Hiyori in exchange for Hiyori's yoyo. However, because Hiyori became sick, and had moved, the promise was not an accomplishment. Their events in the childhood seem to be related to Hiyori's showing up in front of them. A painful love story of Kenji and two girls progresses.