Humanity is under attack by demonic creatures called Oni. Unable to fight back by any other means, the scientist Dr. Saotome creates a series of giant robots that harness the mysterious power of Getter Rays, giving them the strength necessary to fight the Oni. The strongest of these is Getter Robo, and Saotome must enlist three very different men to pilot it - martial artist Ryoma Nagare, criminal leader Hayato Jin, and monk Benkei Musashibou. Together, the Getter Team fights to end the Oni menace forever. (Source: ANN)

Earth started space colonization by creating the Next Colonies. Next later rebelled, and created the Next Government. The rebellion became a war, and the multi-purpose Metal Vehicles, MVs for short, were changed for battle purposes. Meanwhile, Terra, an Earth Rebellion force, started creating more trouble for Earth. Now, a mysterious MV-like being, S.A.C ("S" for short), is loose, and Next wants it so that they can win the war. Terra's psychic leader, Hal, has been sensing "S", and wants to know more about the power it has. The future of these three groups will be up to a bunch of outlaws who live on the abandoned Next 7 colony, though no one knows that yet...

The brilliant Dr. Azuma created many robots to aid humankind. However, during a thunderstorm his lab was struck by lightning, corrupting the programming of one of his robots, BK-1, who renames himself Braiking Boss and declares that instead of serving mankind, mankind will now serve him! He brings other robots together into an overwhelming army bent on enslaving the human race. Tetsuya, Dr. Azuma's son, asks his father to turn him into an indestructible android so that he will have the power to destroy the threat his father inadvertently created. Shortly thereafter, Braiking Boss captures Dr. Azuma and his wife. Tetsuya, now renamed Casshern, sets out to turn the tide of the war and rescue his parents, with the help of his girlfriend, Luna, and robot dog, Friender.

Najica Hiiragi, perfumer and secret agent, is sent out on a number of recovery missions to round up rogue humaritts, androids with combat abilities. Najica is assigned a humaritt partner, Lila, whom Najica is to groom as an agent and receive assistance from along the way. As Najica grows to accept Lila, each new mission they embark on reveals more and more about the capabilities and mysterious origins of the humaritts. (Source: ANN)