Zunko Tohoku can make any mochi into delicious zunda mochi by shooting it with her Zunda Arrow. Along with Kiritan Tohoku, Itako Tohoku, Usagi Chūgoku, Metan Shikoku, and Sora Kyushu, she enjoys eating zunda mochi while being full of happiness. Chanko Ōedo conversely leads the Natto Factory along with her companions Tsurugi Chubu, Shinobi Kansai, Awamo Okinawa, and Meron Hokkaido. Even though zunda and natto use the same type of bean, the edamame used in zunda and the soy beans used in natto are harvested at different times, with edamame being harvested first. As a result, the members of the Natto Factory are afraid of a decrease in the quantity of soybeans harvested. Chanko sends Awamo Okinawa and Meron Hokkaido to Zunko's house to assassinate her, but a third power makes their appearance.

Fam and Ihrie are willing to do almost anything to make a buck. So when these debt-driven damsels discover the potential profits to be hand in recovering a particularly dangerous mystical object, it means mortal peril for an entire civilization. There's no guarantee that they'll live long enough to squander the fabulous wealth they've been promised, and danger lurks around every turn as they cross dark seas in pursuit of legendary evil. Haunted by an unspeakable curse, plagued by doomsday prophecies, plotted against by untrustworthy traveling companions and looked in desperate race to gain the Ultimate Power, Fam and Ihrie are the Ruin Explorers!

Not long after forming their partnership, detectives Ron Kamonohashi and Totomaru Isshiki have proven adept at solving various cases together. However, the two are further motivated to continue their work when they discover that the House of M—an infamous crime syndicate—orchestrated Ron's expulsion from the prestigious Detective Training Academy BLUE five years prior. It appears that this group is also linked to Ron's mysterious ability that causes those around him to lose their lives, a phenomenon which Ron is desperate to stop. A member of the House of M soon starts to commit boastful serial murders around Shibuya as an act of provocation toward Ron. Consequently, the investigative pair must do their best to apprehend the culprit for the sake of justice as well as learning more about Ron's dark past and present condition.

Second season of Mewkledreamy.