For hearing-impaired university student Yuki Itose, silence has been a natural part of life since birth. Her world is small and isolated; she commutes to campus, interacts with her best friend Rin Fujishiro, and communicates through writing and text messages—a lifestyle that offers little to no change. One day, during her commute, Yuki meets fellow student Itsuomi Nagi, a multilingual travel enthusiast and friend of Rin. When Itsuomi learns of Yuki's condition, he takes it in stride, moving Yuki's heart. From this one simple gesture, Yuki and Itsuomi's lives start changing day by day as they let each other into their own worlds.

At True Cross Academy, Rin Okumura unknowingly comes across the first signs that something is amiss; ordinary people have been gaining the ability to perceive the invisible creatures that roam the human realm, Assiah. While Rin sees this as an opportunity to make a new friend, his twin brother, Yukio, is more burdened than ever. Swamped with his education, exorcist duties, and teaching position, Yukio has remained silent about his awakened powers, unable to understand their scale or significance. While Rin and his friends prepare for the annual Exorcist Certification Exam, the True Cross Order has uncovered the first artificial gate to the demonic realm of Gehenna. Witnessing its size and the advanced technology that made it possible, the exorcists realize they are now dealing with the Illuminati, an extremely wealthy and powerful organization. Moreover, the inscrutable Illuminati have planted three spies in the True Cross Order—and one may be hiding among the aspiring exorcists sworn to protect mankind from the demonic threat.

After an eventful winter break, Kyoutarou Ichikawa and Anna Yamada reunite with a stronger bond. They continue to grow in their own ways, with Yamada taking on more challenging photoshoots and Ichikawa maturing both physically and emotionally as he tackles his affections for Yamada. However, spending time together outside of school allows for their relationship to deepen, and it becomes increasingly difficult to deny their budding romantic feelings. Grappling with these unexpected and new emotions, Ichikawa and Yamada realize that, with the passage of time, their relationship is bound to change—and they must ultimately decide whether they wish to remain close friends or finally become a couple.

After Mash Burnedead's clash with Magia Lupus, the secret about his powers is now out in the open. The short-lived celebration ends when the Bureau of Magic summons Mash before an audience of Divine Visionaries, who collectively decree Mash should reap the consequences and die. However, an evil shadow organization called Innocent Zero hijacks the inquiry to demand that Mash be kept alive. Mash proves that he is capable of dealing with Innocent Zero, but the Divine Visionaries' verdict remains unchanged. Luckily, Mash finds unexpected allies in Divine Visionary Rayne Ames and Headmaster Wahlberg Baigan, and they successfully defer his execution until Innocent Zero is defeated. Mash is now allowed to live under one condition: he must be selected as the Divine Visionary candidate by the year's end.