Awaking to absolute chaos and carnage while on a school trip, Yogiri Takatou discovers that everyone in his class has been transported to another world! He had somehow managed to sleep through the entire ordeal himself, missing out on the Gift — powers bestowed upon the others by a mysterious Sage who appeared to transport them. Even worse, he and another classmate were ruthlessly abandoned by their friends, left as bait to distract a nearby dragon. Although not terribly bothered by the thought of dying, he reluctantly decides to protect his lone companion. After all, a lowly Level 1000 monster doesn't stand a chance against his secret power to invoke Instant Death with a single thought! If he can stay awake long enough to bother using it, that is...

Cursed by a witch, the feral and tempestuous Guideau tenaciously searches for the culprit so she can exact revenge. To this end, she joins the Order of Magical Resonance, an organization that deals with everything connected to magic. The Order agrees to work with Guideau in return for her help solving the myriad of magic-related cases occurring across the world. The Order's suave and mysterious mage Ashaf accompanies Guideau for the sake of successfully completing missions. As the pair traverses the land in search of that unknown witch, their experience with the fantastical world of magic grows ever more peculiar the further they advance in their journey.

After his high school graduation, Yuuki Wakura realizes it has been five years since his sister's disappearance during a "Mato disaster." Throughout Japan, mysterious entrances have opened to a dimension called "Mato"—a demonic metropolis filled with disastrous monsters known as the "Shuuki" that threaten the safety of humans. However, a new hope arose, as the discovery of a Mato fruit that grants supernatural abilities exclusively to women allowed them to fight against the Shuuki. Due to this, a new matriarchal government was formed, establishing a female organization called the Anti-Demon Corps, which caused men to fall to the bottom of society. When Yuuki suddenly finds himself in Mato, he is unable to escape on his own. But just as he anticipates a gruesome end by the Shuuki, a girl in a militia outfit appears and protects him. As the chief of the Seventh Unit of the Anti-Demon Corps, Kyouka Uzen is ambitious yet devalued by her own peers due to her power being deemed unusual. Now in a life-or-death situation, Kyouka takes the opportunity to find out the true potential of her superpower by using Yuuki: in order to defeat the Shuuki, he has to become her slave.

Gekkan Mousou Kagaku is set in Most City in an unknown country in a small publishing house that prints a monthly magazine about the most outlandish of things. Everything changes when the staff of the magazine, editor-in-chief Tarou, his assistant Jirou and dog Saburou, meet with scientist Gorou Satou...