Death City is home to the famous Death Weapon Meister Academy, a technical academy headed by the Shinigami—Lord Death himself. Its mission: to raise "Death Scythes" for the Shinigami to wield against the many evils of their fantastical world. These Death Scythes, however, are not made from physical weapons; rather, they are born from human hybrids who have the ability to transform their bodies into Demon Weapons, and only after they have consumed the souls of 99 evil beings and one witch's soul. Soul Eater Evans, a Demon Scythe who only seems to care about what's cool, aims to become a Death Scythe with the help of his straight-laced wielder, or meister, Maka Albarn. The contrasting duo work and study alongside the hot headed Black☆Star and his caring weapon Tsubaki, as well as the Shinigami's own son, Death the Kid, an obsessive-compulsive dual wielder of twin pistols Patty and Liz. Soul Eater follows these students of Shibusen as they take on missions to collect souls and protect the city from the world's threats while working together under the snickering sun to become sounder in mind, body, and soul. [Written by MAL Rewrite]

Soul Eater NOT! is a spin-off and side story that takes place one year prior to the events of the original Soul Eater. At the Death Weapon Meister Academy, humans born with the power to transform into weapons and those with the power to wield these weapons (Meisters) train to hone their natural talent. The characters of the main series are enrolled in the Especially Advantaged Talent class, where they train to become warriors of justice capable of defeating what threats prey on innocent lives—or even the entire world. Other students at the DWMA are less talented. Members of the Normally Overcome Target class focus less on being warriors of justice and more on controlling their powers so they don't hurt themselves or anyone around them. Tsugumi Harudori, a new halberd-transforming student, meets Meisters Meme Tatane and Anya Hepburn and quickly grows indecisive about which of the two new friends should be her partner. As they learn to use these powers and settle in, their lives as everyday students will be far from normal.

In the midst of the Fifth Holy Grail War, Caster sets her plans into motion, beginning with the capture of Shirou's Servant Saber. With the witch growing ever more powerful, Rin and Archer determine she is a threat that must be dealt with at once. But as the balance of power in the war begins to shift, the Master and Servant find themselves walking separate ways. Meanwhile, despite losing his Servant and stumbling from injuries, Shirou ignores Rin's warning to abandon the battle royale, forcing his way into the fight against Caster. Determined to show his resolve in his will to fight, Shirou's potential to become a protector of the people is put to the test. Amidst the bloodshed and chaos, the motivations of each Master and Servant are slowly revealed as they sacrifice everything in order to arise as the victor and claim the Holy Grail. [Written by MAL Rewrite]

The Holy Grail War is a battle royale among seven magi who serve as Masters. Masters, through the use of the command seals they are given when they enter the war, command Heroic Spirits known as Servants to fight for them in battle. In the Fifth Holy Grail War, Rin Toosaka is among the magi entering the competition. With her Servant, Archer, she hopes to obtain the ultimate prize—the Holy Grail, a magical artifact capable of granting its wielder any wish. One of Rin's classmates, Emiya Shirou, accidentally enters the competition and ends up commanding a Servant of his own known as Saber. As they find themselves facing mutual enemies, Rin and Shirou decide to form a temporary alliance as they challenge their opponents in the Holy Grail War. [Written by MAL Rewrite]